Sign in or Register   Sign in or Register
  |  

Mouse Anti-BAZ1A Recombinant Antibody (1F6) (CBMAB-A0719-LY)

The product is antibody recognizes BAZ1A. The antibody 1F6 immunoassay techniques such as: WB, ELISA.
See all BAZ1A antibodies
Published Data
Fig. 1 Immunoprecipitation assays were done to compare the binding capability between hSNF2H and different binding partners.
...View More

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F6
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
BAZ1A (NP_038476, 1457 a.a. ~ 1556 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
bromodomain adjacent to zinc finger domain, 1A
Entrez Gene ID
11177
UniProt ID
Q9NRL2
Alternative Names
ACF1; DKFZp586E0518; FLJ14383; WALp1; WCRF180; hACF1
Function
Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.
Component of the histone-fold protein complex CHRAC complex which facilitates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.
Biological Process
Chromatin remodeling Source: BHF-UCL
DNA-dependent DNA replication Source: UniProtKB
Histone acetylation Source: GOC
Regulation of transcription by RNA polymerase II Source: BHF-UCL
Cellular Location
Nucleus. May target the CHRAC complex to heterochromatin.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-BAZ1A Recombinant Antibody (1F6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare