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Mouse Anti-BIN1 Recombinant Antibody (CBYY-0589) (CBMAB-0592-YY)

This product is mouse antibody that recognizes BIN1. The antibody CBYY-0589 can be used for immunoassay techniques such as: ELISA, WB, IHC-P, FC
Host Species
Mouse
Application
ELISA, WB, IHC-P, FC
Immunogen
Recombinant fragment of human BIN1 (AA: 189-398) expressed in E. Coli
Antibody Isotype
IgG2b
Specificity
Human, Mouse
Clone
CBYY-0589
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes several isoforMouse of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. IsoforMouse that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. IsoforMouse that are expressed in muscle and ubiquitously expressed isoforMouse localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforMouse. Aberrant splice variants expressed in tumor cell lines have also been described.
Alternative Name
Bridging Integrator 1; Amphiphysin II; Box-Dependent Myc-Interacting Protein 1; Amphiphysin-Like Protein; AMPHL; Box Dependant MYC Interacting Protein 1;
Entrez Gene ID
Human274
Mouse30948
UniProt ID
HumanO00499
MouseO08539
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0592-YY
Conjugates
Size
Price $
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Second antibody and isotype control