Mouse Anti-BOD1L1 Recombinant Antibody (CBXF-1700) (CBMAB-F3235-CQ)

Name: Mouse Anti-BOD1L1 Recombinant Antibody (CBXF-1700)
SKU: CBMAB-F3235-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-1700

Application

WB, IP, IF, E

Immunogen

Amino acids 466-530 mapping within an internal region of FAM44A of human origin.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

0.09% sodium azide

Concentration

0.2 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Biorientation Of Chromosomes In Cell Division 1 Like 1

Introduction

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM (PubMed:26166705). Does not regulate spindle orientation (PubMed:26166705).

Entrez Gene ID

259282

UniProt ID

Q8NFC6

Alternative Names

Biorientation Of Chromosomes In Cell Division 1 Like 1; Biorientation Of Chromosomes In Cell Division 1-Like; Family With Sequence Similarity 44, Member A; FAM44A; BOD1L; Biorientation Of Chromosomes In Cell Division Protein 1-Like 1; KIAA1327;

Function

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBH1 and BLM (PubMed:26166705).
Does not regulate spindle orientation (PubMed:26166705).

Biological Process

Cellular response to DNA damage stimulus Source: UniProtKB
DNA repair Source: UniProtKB-KW
Negative regulation of phosphoprotein phosphatase activity Source: GO_Central
Replication fork processing Source: UniProtKB

Cellular Location

Chromosome. Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-BOD1L1 Recombinant Antibody (2A1) (CAT#: CBMAB-A2822-LY)

Isotype control

For research use only. Not intended for any clinical use.

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