BOD1L1

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM (PubMed:26166705). Does not regulate spindle orientation (PubMed:26166705).

Full Name

Biorientation Of Chromosomes In Cell Division 1 Like 1

Function

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBH1 and BLM (PubMed:26166705).
Does not regulate spindle orientation (PubMed:26166705).

Biological Process

Cellular response to DNA damage stimulus Source: UniProtKB
DNA repair Source: UniProtKB-KW
Negative regulation of phosphoprotein phosphatase activity Source: GO_Central
Replication fork processing Source: UniProtKB

Cellular Location

Chromosome. Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection.

Anti-BOD1L1 antibodies

Mouse Anti-BOD1L1 Recombinant Antibody (CBXF-2733) (CBMAB-F3450-CQ)

Datasheet

SDS

Target: BOD1L1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-2733

Application*: E, WB

Mouse Anti-BOD1L1 Recombinant Antibody (CBXF-1700) (CBMAB-F3235-CQ)

Datasheet

SDS

Target: BOD1L1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-1700

Application*: WB, IP, IF, E

Mouse Anti-BOD1L1 Recombinant Antibody (2A1) (CBMAB-A2822-LY)

Datasheet

SDS

Target: BOD1L1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2A1

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)