BOD1L1

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM (PubMed:26166705). Does not regulate spindle orientation (PubMed:26166705).

Full Name

Biorientation Of Chromosomes In Cell Division 1 Like 1

Function

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBH1 and BLM (PubMed:26166705).
Does not regulate spindle orientation (PubMed:26166705).

Biological Process

Cellular response to DNA damage stimulus Source: UniProtKB
DNA repair Source: UniProtKB-KW
Negative regulation of phosphoprotein phosphatase activity Source: GO_Central
Replication fork processing Source: UniProtKB

Cellular Location

Chromosome. Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection.