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BOD1L1

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM (PubMed:26166705). Does not regulate spindle orientation (PubMed:26166705).

Full Name

Biorientation Of Chromosomes In Cell Division 1 Like 1

Function

Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBH1 and BLM (PubMed:26166705).
Does not regulate spindle orientation (PubMed:26166705).

Biological Process

Cellular response to DNA damage stimulus Source: UniProtKB
DNA repair Source: UniProtKB-KW
Negative regulation of phosphoprotein phosphatase activity Source: GO_Central
Replication fork processing Source: UniProtKB

Cellular Location

Chromosome. Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection.

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Anti-BOD1L1 antibodies

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Mouse Anti-BOD1L1 Recombinant Antibody (CBXF-1700) (CBMAB-F3235-CQ)

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Target: BOD1L1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXF-1700

Application*: WB, IP, IF, E

Mouse Anti-BOD1L1 Recombinant Antibody (2A1) (CBMAB-A2822-LY)

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Target: BOD1L1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2A1

Application*: WB, E

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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