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Mouse Anti-BOLL Recombinant Antibody (V2-611636) (CBMAB-A0849-LY)

The product is antibody recognizes BOLL. The antibody 1A2 immunoassay techniques such as: WB, ELISA.
See all BOLL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-611636
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
BOLL (NP_149019, 185 a.a. ~ 283 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
bol, boule-like (Drosophila)
Introduction
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Entrez Gene ID
66037
UniProt ID
Q8N9W6
Function
Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity).
Biological Process
3'-UTR-mediated mRNA stabilization Source: GO_Central
Cell differentiation Source: UniProtKB-KW
Meiotic cell cycle Source: MGI
Multicellular organism development Source: UniProtKB-KW
Positive regulation of translational initiation Source: UniProtKB
Spermatogenesis Source: UniProtKB-KW
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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