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Rabbit Anti-BORA Recombinant Antibody (D2B9) (CBMAB-CP0015-LY)

The product is antibody recognizes BORA. The antibody D2B9 immunoassay techniques such as: WB,IP,FC.
See all BORA antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
D2B9
Antibody Isotype
IgG
Application
WB, IP, FC

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a recombinant protein specific to the carboxy terminus of human Bora protein.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
BORA aurora kinase A activator
Introduction
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).
Entrez Gene ID
79866
UniProt ID
Q6PGQ7
Alternative Names
C13orf34
Function
Required for the activation of AURKA at the onset of mitosis.
Biological Process
Activation of protein kinase activity Source: GO_Central
Cell division Source: UniProtKB-KW
G2/M transition of mitotic cell cycle Source: Reactome
Regulation of mitotic nuclear division Source: UniProtKB
Regulation of mitotic spindle organization Source: UniProtKB
Regulation of protein localization Source: UniProtKB
Cellular Location
Cytosol; Nucleus; Cytoplasm
PTM
Phosphorylated by AURKA.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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