Sign in or Register
  • Home
  • BORA
  • Rabbit Anti-BORA Recombinant Antibody (CBYY-0722)

Rabbit Anti-BORA Recombinant Antibody (CBYY-0722) (CBMAB-0725-YY)

See all BORA antibodies
Go to compare Compare Online Inquiry
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
CBYY-0722
Application
WB
Immunogen
Protein corresponding to Human BORA (aa 274-456).
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1-2 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Concentration
0.5 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
BORA aurora kinase A activator
Introduction
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis .
Entrez Gene ID
Human79866
Mouse77744
Rat306102
UniProt ID
HumanQ6PGQ7
MouseQ8BS90
RatQ5M864
Alternative Names
Bora, Aurora Kinase A Activator; C13orf34; Chromosome 13 Open Reading Frame 34; Protein Aurora Borealis; HsBora;
Function
Required for the activation of AURKA at the onset of mitosis.
Biological Process
Activation of protein kinase activity Source: GO_Central
Cell division Source: UniProtKB-KW
G2/M transition of mitotic cell cycle Source: Reactome
Regulation of mitotic nuclear division Source: UniProtKB
Regulation of mitotic spindle organization Source: UniProtKB
Regulation of protein localization Source: UniProtKB
Cellular Location
Cytosol; Nucleus; Cytoplasm
PTM
Phosphorylated by AURKA.

Mamoor, S. (2021). Over-expression of bora, aurora kinase A activator in human endometrial cancer.

Tavernier, N., Thomas, Y., Vigneron, S., Maisonneuve, P., Orlicky, S., Mader, P., ... & Pintard, L. (2021). Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry. Nature communications, 12(1), 1-22.

Parrilla, A., Barber, M., Majem, B., Castellví, J., Morote, J., Sánchez, J. L., ... & Santamaria, A. (2020). Aurora borealis (Bora), which promotes Plk1 activation by Aurora A, has an oncogenic role in ovarian cancer. Cancers, 12(4), 886.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-BORA Recombinant Antibody (CBYY-0722)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-Bora Recombinant Antibody (CBYY-1755) (CAT#: CBMAB-2104-YY)

Mouse Anti-Bora Recombinant Antibody (CBYY-0726) (CAT#: CBMAB-0729-YY)

Rabbit Anti-BORA Recombinant Antibody (D2B9) (CAT#: CBMAB-CP0015-LY)

Mouse Anti-Bora Recombinant Antibody (CBYY-1756) (CAT#: CBMAB-2105-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry