Mouse Anti-BRDG1 Recombinant Antibody (5A10) (CBMAB-A0881-LY)

Name: Mouse Anti-BRDG1 Recombinant Antibody (5A10)
SKU: CBMAB-A0881-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

5A10

Application

WB, E

Immunogen

BRDG1 (NP_036240, 186 a.a. ~ 293 a.a) partial recombinant protein with GST tag.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

signal transducing adaptor family member 1

Introduction

The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity. [provided by RefSeq]

Entrez Gene ID

26228

UniProt ID

Q9ULZ2

Alternative Names

BRDG1; STAP-1

Biological Process

Cellular response to lipopolysaccharide Source: Ensembl
Negative regulation of macrophage chemotaxis Source: Ensembl
Negative regulation of macrophage colony-stimulating factor signaling pathway Source: Ensembl
Negative regulation of microglial cell migration Source: Ensembl
Negative regulation of phosphorylation Source: Ensembl
Negative regulation of ruffle assembly Source: Ensembl
Positive regulation of actin cytoskeleton reorganization Source: Ensembl
Positive regulation of gene expression Source: Ensembl
Positive regulation of microglial cell activation Source: Ensembl
Positive regulation of microglial cell mediated cytotoxicity Source: Ensembl
Positive regulation of phagocytosis, engulfment Source: Ensembl

Cellular Location

Nucleoplasm; Intracellular membrane-bounded organelle

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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