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Mouse Anti-BRDG1 Recombinant Antibody (5A10) (CBMAB-A0881-LY)

The product is antibody recognizes BRDG1. The antibody 5A10 immunoassay techniques such as: WB, ELISA.
See all BRDG1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5A10
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
BRDG1 (NP_036240, 186 a.a. ~ 293 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
signal transducing adaptor family member 1
Introduction
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity. [provided by RefSeq]
Entrez Gene ID
26228
UniProt ID
Q9ULZ2
Alternative Names
BRDG1; STAP-1
Biological Process
Cellular response to lipopolysaccharide Source: Ensembl
Negative regulation of macrophage chemotaxis Source: Ensembl
Negative regulation of macrophage colony-stimulating factor signaling pathway Source: Ensembl
Negative regulation of microglial cell migration Source: Ensembl
Negative regulation of phosphorylation Source: Ensembl
Negative regulation of ruffle assembly Source: Ensembl
Positive regulation of actin cytoskeleton reorganization Source: Ensembl
Positive regulation of gene expression Source: Ensembl
Positive regulation of microglial cell activation Source: Ensembl
Positive regulation of microglial cell mediated cytotoxicity Source: Ensembl
Positive regulation of phagocytosis, engulfment Source: Ensembl
Cellular Location
Nucleoplasm; Intracellular membrane-bounded organelle
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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