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Mouse Anti-ATRAID Recombinant Antibody (1D2) (CBMAB-A0975-LY)

The product is antibody recognizes C2orf28. The antibody 1D2 immunoassay techniques such as: ELISA.
See all ATRAID antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D2
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
C2orf28 (AAH11006, 1 a.a. ~ 171 a.a) full-length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
All-Trans Retinoic Acid Induced Differentiation Factor
Introduction
This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
APR--3; APR-3; APR3; HSPC013; PRO240; p18
Function
Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway.
Biological Process
Cell differentiation Source: UniProtKB-KW
Negative regulation of cellular protein catabolic process Source: UniProtKB
Negative regulation of osteoblast proliferation Source: UniProtKB
Positive regulation of bone mineralization Source: UniProtKB
Positive regulation of osteoblast differentiation Source: UniProtKB
Regulation of gene expression Source: UniProtKB
Cellular Location
Nucleus envelope; Cell membrane. Colocalizes with NELL1 on the nuclear envelope and the perinuclear region (PubMed:21723284).
Topology
Extracellular: 31-199 aa
Helical: 200-220 aa
Cytoplasmic: 221-229 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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