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Mouse Anti-C4BPB (AA 1-251) Recombinant Antibody (CBFYC-0648) (CBMAB-C0702-FY)

This product is mouse antibody that recognizes C4BPB. The antibody CBFYC-0648 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all C4BPB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0648
Antibody Isotype
IgG2a, k
Application
ELISA, IP, WB

Basic Information

Immunogen
Full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-251

Target

Full Name
C4BPB
Introduction
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids.
Entrez Gene ID
UniProt ID
Alternative Names
C4BP
Function
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Biological Process
Blood coagulation Source: ProtInc
Complement activation, classical pathway Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Negative regulation of complement activation, classical pathway Source: BHF-UCL
Positive regulation of protein catabolic process Source: BHF-UCL
Regulation of complement activation Source: Reactome
Regulation of opsonization Source: BHF-UCL
Response to symbiotic bacterium Source: BHF-UCL
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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