Mouse Anti-C4BPB Recombinant Antibody (CBFYC-0648) (CBMAB-C0702-FY)

Name: Mouse Anti-C4BPB Recombinant Antibody (CBFYC-0648)
SKU: CBMAB-C0702-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYC-0648

Application

WB, IP, IF, E

Immunogen

Amino acids 82-252 mapping at the C-terminus of C4BPβ of human origin.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

0.09% sodium azide

Concentration

0.2 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-251

More Infomation

Target

Full Name

C4BPB

Introduction

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids.

Entrez Gene ID

725

UniProt ID

P20851

Alternative Names

C4BP

Function

Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

Biological Process

Blood coagulation Source: ProtInc
Complement activation, classical pathway Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Negative regulation of complement activation, classical pathway Source: BHF-UCL
Positive regulation of protein catabolic process Source: BHF-UCL
Regulation of complement activation Source: Reactome
Regulation of opsonization Source: BHF-UCL
Response to symbiotic bacterium Source: BHF-UCL

Cellular Location

Secreted

Jiang, T. T., Shi, L. Y., Wei, L. L., Li, X., Yang, S., Wang, C., ... & Li, J. C. (2017). Serum amyloid A, protein Z, and C4b-binding protein β chain as new potential biomarkers for pulmonary tuberculosis. PloS one, 12(3), e0173304.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

C4BPB Matched Antibody Pair (158) (CAT#: APMAB-158LY)

C4BPB Matched Antibody Pair (159) (CAT#: APMAB-159LY)

C4BPB Matched Antibody Pair (160) (CAT#: APMAB-160LY)

Related Products

C4BPB Matched Antibody Pair (159) (CAT#: APMAB-159LY)

Mouse Anti-C4BPB Recombinant Antibody (CBXC-0019) (CAT#: CBMAB-C5935-CQ)

C4BPB Matched Antibody Pair (160) (CAT#: APMAB-160LY)

Rabbit Anti-C4BPB Recombinant Antibody (CBXC-0018) (CAT#: CBMAB-C5934-CQ)

C4BPB Matched Antibody Pair (158) (CAT#: APMAB-158LY)

Rabbit Anti-C4BPB Recombinant Antibody (CBLC022-LY) (CAT#: CBMAB-C9546-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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