Rabbit Anti-C4BPB Recombinant Antibody (CBXC-0018) (CBMAB-C5934-CQ)

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
CBXC-0018
Application
IP, IF, IH, IC, WB
Immunogen
A synthesized peptide derived from human C4 binding protein.
Host Species
Rabbit
Specificity
Human, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:1,000
IP1:60
IF(ICC)1:50-1:200
IHC1:100-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 0.4-0.5mg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
C4BPB
Entrez Gene ID
UniProt ID
Alternative Names
C4BP
Function
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Biological Process
Blood coagulation Source: ProtInc
Complement activation, classical pathway Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Negative regulation of complement activation, classical pathway Source: BHF-UCL
Positive regulation of protein catabolic process Source: BHF-UCL
Regulation of complement activation Source: Reactome
Regulation of opsonization Source: BHF-UCL
Response to symbiotic bacterium Source: BHF-UCL
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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