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Rabbit Anti-CA14 Recombinant Antibody (BA0138) (CBMAB-0130CQ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
BA0138
Antibody Isotype
IgG
Application
E, P, IF

Basic Information

Immunogen
Recombinant Human CA14 protein.
Host Species
Rabbit
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
ELISA1:5,000-1:10,000
IHC-P1:100-1:500
IF(ICC)1:20-1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
carbonic anhydrase 14
Introduction
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
Entrez Gene ID
Human23632
Mouse23831
Rat791259
UniProt ID
HumanQ9ULX7
MouseQ9WVT6
RatA2IBE0
Alternative Names
Carbonic Anhydrase XIV; Carbonate Dehydratase XIV; CA-XIV; Carbonic Dehydratase; EC 4.2.1.1; CAXiV
Function
Reversible hydration of carbon dioxide.
Biological Process
Bicarbonate transport Source: Reactome
One-carbon metabolic process Source: GO_Central
Cellular Location
Membrane
Topology
Extracellular: 16-290 aa
Helical: 291-311 aa
Cytoplasmic: 312-337 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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