CA14
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
Full Name
carbonic anhydrase 14
Function
Reversible hydration of carbon dioxide.
Biological Process
Bicarbonate transport Source: Reactome
One-carbon metabolic process Source: GO_Central
One-carbon metabolic process Source: GO_Central
Cellular Location
Membrane
Topology
Extracellular: 16-290 aa
Helical: 291-311 aa
Cytoplasmic: 312-337 aa
Helical: 291-311 aa
Cytoplasmic: 312-337 aa
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Anti-CA14 antibodies
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Target: CA14
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 110
Application*: E
Target: CA14
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 33
Application*: E, WB
Target: CA14
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 004
Application*: E
Target: CA14
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Horse, Cattle, Pig
Clone: EG444
Application*: E, WB, IF, IP
Target: Carbonic Anhydrase XIV
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-C0945
Application*: E
Target: CA14
Host: Mouse
Antibody Isotype: IgG2a, ĸ
Specificity: Human, Mouse, Rat, Horse, Cattle, Pig
Clone: CBYY-C0834
Application*: E, WB, IF, IP
Target: CA14
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Horse, Cattle, Pig
Clone: CBFYC-0689
Application*: E, WB, IF, IP
Target: CA14
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: BA0138
Application*: E, P, IF
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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