Mouse Anti-CACTIN Recombinant Antibody (CBLC055-LY) (CBMAB-C9623-LY)
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Basic Information
| Application | Note |
| WB | 1:100-1:1,000 |
| IP | 1-2 µg per 100-500 µg of total protein (1 ml of cell lysate) |
| IF(ICC) | 1:50-1:500 |
| ELISA | 1:100-1:1,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Acts as negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (PubMed:20829348, PubMed:26363554).
Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli (PubMed:20829348, PubMed:26363554).
Cellular response to lipopolysaccharide Source: UniProtKB
Cellular response to tumor necrosis factor Source: UniProtKB
Innate immune response Source: UniProtKB-KW
mRNA cis splicing, via spliceosome Source: GO_Central
mRNA splicing, via spliceosome Source: UniProtKB
Multicellular organism development Source: UniProtKB-KW
Negative regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
Negative regulation of innate immune response Source: GO_Central
Negative regulation of interferon-beta production Source: UniProtKB
Negative regulation of interleukin-8 production Source: UniProtKB
Negative regulation of lipopolysaccharide-mediated signaling pathway Source: UniProtKB
Negative regulation of NF-kappaB transcription factor activity Source: UniProtKB
Negative regulation of protein phosphorylation Source: UniProtKB
Negative regulation of toll-like receptor signaling pathway Source: UniProtKB
Negative regulation of tumor necrosis factor production Source: UniProtKB
Negative regulation of type I interferon-mediated signaling pathway Source: UniProtKB
Regulation of gene expression Source: GO_Central
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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