Mouse Anti-CALML3 Recombinant Antibody (2A11) (CBMAB-C4578-LY)

Name: Mouse Anti-CALML3 Recombinant Antibody (2A11)
SKU: CBMAB-C4578-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2A11

Application

ELISA, WB, IF, IHC

Immunogen

CALML3 (AAH31889, 1 a.a. ~ 149 a.a) full-length recombinant protein with GST tag.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
IF(ICC)	10 µg/ml
IHC	3 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Calmodulin Like 3

Entrez Gene ID

810

UniProt ID

P27482

Function

May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates.

Cellular Location

Extracellular exosome

Chen, G., Yu, C., Tang, Z., Liu, S., An, F., Zhu, J., ... & Zhang, S. (2019). Metformin suppresses gastric cancer progression through calmodulin‑like protein 3 secreted from tumor‑associated fibroblasts. Oncology reports, 41(1), 405-414.

Jia, Y., Qin, Q., Fang, C. P., Shen, W., Sun, T. T., Huang, Y. L., ... & Deng, A. M. (2018). UVB induces apoptosis via downregulation of CALML3-dependent JNK1/2 and ERK1/2 pathways in cataract. International journal of molecular medicine, 41(5), 3041-3050.

Qin, S., Ingle, J. N., Liu, M., Yu, J., Wickerham, D. L., Kubo, M., ... & Wang, L. (2017). Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion. Breast Cancer Research, 19(1), 1-14.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

CALML3 Matched Antibody Pair (170) (CAT#: APMAB-170LY)

CALML3 Matched Antibody Pair (171) (CAT#: APMAB-171LY)

Related Products

CALML3 Matched Antibody Pair (171) (CAT#: APMAB-171LY)

Rabbit Anti-CALML3 Recombinant Antibody (004) (CAT#: CBMAB-C1505-LY)

Mouse Anti-CALML3 Recombinant Antibody (03) (CAT#: CBMAB-C1696-LY)

CALML3 Matched Antibody Pair (170) (CAT#: APMAB-170LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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