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Mouse Anti-CAPZA3 Recombinant Antibody (CBL-LY-002) (CBMAB-C9401-LY)

This product is antibody recognizes CAPZA3. The antibody CBL-LY-002 immunoassay techniques such as: ELISA, WB.
See all CAPZA3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBL-LY-002
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Capping Actin Protein Of Muscle Z-Line Alpha Subunit 3
Introduction
CAPZA1 (Capping Actin Protein Of Muscle Z-Line Alpha Subunit 1) is a Protein Coding gene. Diseases associated with CAPZA1 include Autosomal Recessive Primary Microcephaly. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include actin binding.
An important paralog of this gene is CAPZA2.
Entrez Gene ID
93661
UniProt ID
Q96KX2
Alternative Names
Capping Actin Protein Of Muscle Z-Line Alpha Subunit 3; Capping Protein (Actin Filament) Muscle Z-Line, Alpha 3; Germ Cell-Specific Protein 3; CapZ Alpha-3; CP-Alpha-3; Gsg3; Testis Tissue Sperm-Binding Protein Li 73n;
Function
F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity).
Biological Process
Actin cytoskeleton organization Source: GO_Central
Actin filament organization Source: Ensembl
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Barbed-end actin filament capping Source: GO_Central
Cytoplasm organization Source: Ensembl
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Spermatid development Source: Ensembl
Cellular Location
Cortical cytoskeleton; F-actin capping protein complex; Cytosol; Nucleus; Membrane; Sperm head
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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