Mouse Anti-CCL19 Recombinant Antibody (CBYY-C1065) (CBMAB-C2502-YY)

C-C Motif Chemokine Ligand 19

C-C Motif Chemokine Ligand 5; SIS-Delta; Regulated Upon Activation, Normally T-Expressed, And Presumably Secreted; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 5; Eosinophil Chemotactic Cytokine; Chemokine (C-C Motif) Ligand 5; T-Cell Specific Protein P288; Beta-Chemokine RANTES; D17S136E; TCP228; SCYA5;

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4.

Activation of JUN kinase activity Source: BHF-UCL
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell communication Source: ProtInc
Cell maturation Source: BHF-UCL
Cellular calcium ion homeostasis Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Cellular response to virus Source: UniProtKB
Chemokine-mediated signaling pathway Source: GO_Central
Cytokine-mediated signaling pathway Source: Reactome
Dendritic cell chemotaxis Source: BHF-UCL
Establishment of T cell polarity Source: BHF-UCL
G protein-coupled receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Immunological synapse formation Source: BHF-UCL
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Mature conventional dendritic cell differentiation Source: BHF-UCL
Monocyte chemotaxis Source: GO_Central
Myeloid dendritic cell chemotaxis Source: BHF-UCL
Negative regulation of dendritic cell apoptotic process Source: BHF-UCL
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cell motility Source: BHF-UCL
Positive regulation of chemotaxis Source: BHF-UCL
Positive regulation of dendritic cell antigen processing and presentation Source: BHF-UCL
Positive regulation of dendritic cell dendrite assembly Source: BHF-UCL
Positive regulation of endocytosis Source: BHF-UCL
Positive regulation of ERK1 and ERK2 cascade Source: BHF-UCL
Positive regulation of glycoprotein biosynthetic process Source: BHF-UCL
Positive regulation of GTPase activity Source: BHF-UCL
Positive regulation of I-kappaB kinase/NF-kappaB signaling Source: BHF-UCL
Positive regulation of interleukin-12 production Source: BHF-UCL
Positive regulation of interleukin-1 beta production Source: BHF-UCL
Positive regulation of JNK cascade Source: BHF-UCL
Positive regulation of neutrophil chemotaxis Source: BHF-UCL
Positive regulation of NIK/NF-kappaB signaling Source: BHF-UCL
Positive regulation of phosphatidylinositol 3-kinase activity Source: BHF-UCL
Positive regulation of protein kinase activity Source: BHF-UCL
Positive regulation of protein kinase B signaling Source: BHF-UCL
Positive regulation of receptor-mediated endocytosis Source: BHF-UCL
Positive regulation of T cell proliferation Source: BHF-UCL
Positive regulation of T-helper 1 cell differentiation Source: BHF-UCL
Positive regulation of tumor necrosis factor production Source: BHF-UCL
Regulation of cell projection assembly Source: BHF-UCL
Release of sequestered calcium ion into cytosol Source: BHF-UCL
Response to nitric oxide Source: BHF-UCL
Response to prostaglandin E Source: BHF-UCL
Response to virus Source: ProtInc
T cell costimulation Source: BHF-UCL

Secreted