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Rabbit Anti-CD2 Recombinant Antibody (118) (CBMAB-C0219-LY)

This product is antibody recognizes CD2. The antibody 118 immunoassay techniques such as: FC.
See all CD2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
118
Antibody Isotype
IgG
Application
FC

Basic Information

Immunogen
Recombinant human CD2 Protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CD2 Molecule
Introduction
CD2 (CD2 Molecule) is a Protein Coding gene. Diseases associated with CD2 include Penis Squamous Cell Carcinoma and Immune Defect Due To Absence Of Thymus. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and receptor activity.
Entrez Gene ID
914
UniProt ID
P06729
Alternative Names
CD2 Molecule; CD2 Antigen (P50), Sheep Red Blood Cell Receptor; T-Cell Surface Antigen T11/Leu-5; Erythrocyte Receptor; Rosette Receptor; LFA-3 Receptor; LFA-2;
Function
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Biological Process
Apoptotic process Source: UniProtKB
Cell-cell adhesion Source: UniProtKB
Cell surface receptor signaling pathway Source: UniProtKB
Heterotypic cell-cell adhesion Source: UniProtKB
Leukocyte migration Source: Reactome
Membrane raft polarization Source: UniProtKB
Natural killer cell activation Source: UniProtKB
Positive regulation of interferon-gamma production Source: UniProtKB
Positive regulation of interleukin-8 production Source: UniProtKB
Positive regulation of myeloid dendritic cell activation Source: UniProtKB
Positive regulation of tumor necrosis factor production Source: UniProtKB
Regulation of T cell differentiation Source: UniProtKB
T cell activation Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 25-209
Helical: 210-235
Cytoplasmic: 236-351
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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