Armenian Hamster Anti-CD209 Recombinant Antibody (22D1) (CBMAB-0973-LY)

Name: Armenian Hamster Anti-CD209 Recombinant Antibody (22D1)
SKU: CBMAB-0973-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Armenian Hamster

Clone

22D1

Application

Blocking, FC, WB, IHC, in vivo

Immunogen

C-terminal peptide of mouse SIGN-R1.

Host Species

Armenian Hamster

Specificity

Mouse

Antibody Isotype

IgG, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Introduction

Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

Entrez Gene ID

69165

UniProt ID

Q8CJ91

Rahimi, N. (2021). C-type lectin CD209L/L-SIGN and CD209/DC-SIGN: cell adhesion molecules turned to pathogen recognition receptors. Biology, 10(1), 1.

Kakar, M. U., Matloob, M., Dai, R., Deng, Y., Ullah, K., Kakar, I. U., ... & Mehboob, M. Z. (2021). In silico screening and identification of deleterious missense SNPs along with their effects on CD-209 gene: An insight to CD-209 related-diseases. Plos one, 16(2), e0247249.

Amraei, R., Yin, W., Napoleon, M. A., Suder, E. L., Berrigan, J., Zhao, Q., ... & Rahimi, N. (2021). CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2. ACS Central Science, 7(7), 1156-1165.

Xue, Y., Li, Q., Park, C. G., Klena, J. D., Anisimov, A. P., Sun, Z., ... & Chen, T. (2021). Proteus mirabilis Targets Atherosclerosis Plaques in Human Coronary Arteries via DC-SIGN (CD209). Frontiers in Immunology, 3351.

Njiri, O. A., Zhang, X., Zhang, Y., Wu, B., Jiang, L., Li, Q., ... & Chen, T. (2020). CD209 C-Type lectins promote host invasion, dissemination, and infection of toxoplasma gondii. Frontiers in immunology, 11, 656.

Deykin, A. V., Kubekina, M. V., Silaeva, Y. Y., Krivonogova, A. S., & Isaeva, A. G. (2020). Using CRISPR/Cas9 for generation the cd209 knockout is a way to get cattle breeds resistant to the bovine leukemia virus (BLV). In E3S Web of Conferences (Vol. 176, p. 01007). EDP Sciences.

He, Y. X., Ye, C. L., Zhang, P., Li, Q., Park, C. G., Yang, K., ... & Chen, T. (2019). Yersinia pseudotuberculosis exploits CD209 receptors for promoting host dissemination and infection. Infection and immunity, 87(1), e00654-18.

Pabalan, N., Chaisri, S., Tabunhan, S., Phumyen, A., Jarjanazi, H., & Steiner, T. S. (2018). Associations of DC-SIGN (CD209) promoter-336G/A polymorphism (rs4804803) with dengue infection: A systematic review and meta-analysis. Acta tropica, 177, 186-193.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

CD209 Matched Antibody Pair (209) (CAT#: APMAB-209LY)

CD209 Matched Antibody Pair (210) (CAT#: APMAB-210LY)

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CD209 Matched Antibody Pair (209) (CAT#: APMAB-209LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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