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Rat Anti-CEACAM2 Recombinant Antibody (CBYY-C0743) (CBMAB-C2179-YY)

This product is rat antibody that recognizes CEACAM2. The antibody CBYY-C0743 can be used for immunoassay techniques such as: FC, CyTOF
See all CEACAM2 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYY-C0743
Antibody Isotype
IgG1
Application
FC, CyTOF

Basic Information

Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Carcinoembryonic antigen related cell adhesion molecule 5
Entrez Gene ID
26367
UniProt ID
Q925P2
Alternative Names
Baculoviral IAP Repeat Containing 2; RING-Type E3 Ubiquitin Transferase BIRC2; TNFR2-TRAF-Signaling Complex Protein 2; NFR2-TRAF Signalling Complex Protein; Cellular Inhibitor Of Apoptosis 1; Inhibitor Of Apoptosis Protein 2; RING Finger Protein 48; Apoptosis Inhibitor 1; IAP Homolog B; Hiap-2; C-IAP1;
Function
Controls energy balance and peripheral insulin action. Involved in the regulation of feeding behavior particularly in the ventromedial nucleus of hypothalamus (VMH) regulation of food intake. Has a role in the regulation of metabolic rate and insulin sensitivity or resistance via effects on brown adipogenesis, sympathetic nervous outflow to brown adipose tissue, spontaneous activity and energy expenditure in skeletal muscle. In case of murine coronavirus (MHV) infection, does probably not serve as functional receptor for the virus.
Isoform 2 may be an adhesion molecule contributing to cell to cell adhesion between elongating spermatids and Sertoli cells within the seminiferous epithelium.
Biological Process
Energy homeostasis Source: MGI
Negative regulation of brown fat cell proliferation Source: MGI
Negative regulation of feeding behavior Source: MGI
Viral process Source: UniProtKB-KW
Cellular Location
Cell membrane; Localizes to sites on the plasma membrane of elongating spermatids where Sertoli cells make contact.
Topology
Extracellular: 35-422
Helical: 423-443
Cytoplasmic: 444-520
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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