Mouse Anti-CFAP298 Recombinant Antibody (2E5) (CBMAB-C5008-LY)

Name: Mouse Anti-CFAP298 Recombinant Antibody (2E5)
SKU: CBMAB-C5008-LY
Rating: 5 (1 reviews)

See all CFAP298 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2E5

Application

FC, IF, WB

Immunogen

Full length human recombinant protein of human C21orf59.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:200-1:1,000
FC	1:100
IF(ICC)	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Cilia And Flagella Associated Protein 298

Entrez Gene ID

56683

UniProt ID

P57076

Function

Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744).
Seems to be important for initiation rather than maintenance of cilium motility (By similarity).
Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity).
May suppress canonical Wnt signaling activity (By similarity).

Biological Process

Cilium assembly Source: UniProtKB
Regulation of cilium movement Source: UniProtKB

Cellular Location

Cytoplasm; Cilium basal body.Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization.

Involvement in disease

Ciliary dyskinesia, primary, 26 (CILD26): The disease is caused by variants affecting the gene represented in this entry. Cilia in nasal epithelia show the absence of both outer and inner dynein-arm components and complete paralysis. A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-CFAP298 Recombinant Antibody (2E5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-CFAP298 Recombinant Antibody (CBWJC-2518) (CAT#: CBMAB-C3589WJ)

Mouse Anti-CFAP298 Recombinant Antibody (CBXC-1895) (CAT#: CBMAB-C3440-CQ)

Mouse Anti-CFAP298 Recombinant Antibody (CBXC-2139) (CAT#: CBMAB-C3439-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry