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Mouse Anti-CHDH Recombinant Antibody (CBXC-1740) (CBMAB-C5547-CQ)


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Published Data
CBMAB-C5547-CQ-1
Mouse Anti-CHDH Recombinant Antibody (CBXC-1740) (CBMAB-C5547-CQ) in WB
CHDH expression in selected cell lines. ...View More
Roci, I., Watrous, J. D., Lagerborg, K. A., Jain, M., & Nilsson, R. (2020). Mapping choline metabolites in normal and transformed cells. Metabolomics, 16, 1-9.
Distributed under Open Access license CC BY 4.0, without modification.

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXC-1740
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 295-594 mapping at the C-terminus of CHDH of human.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Choline Dehydrogenase
Introduction
The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date.
Entrez Gene ID
55349
UniProt ID
Q8NE62
Alternative Names
Choline Dehydrogenase; EC 1.1.99.1; CDH; CHD; Choline Dehydrogenase, Mitochondrial;
Biological Process
Choline catabolic process Source: Reactome
Glycine betaine biosynthetic process from choline Source: UniProtKB-UniPathway
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

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