Mouse Anti-CHI3L2 Recombinant Antibody (CBYY-C0496) (CBMAB-C1481-YY)

Name: Mouse Anti-CHI3L2 Recombinant Antibody (CBYY-C0496)
SKU: CBMAB-C1481-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-C0496

Application

WB, FC

Immunogen

Recombinant human CHI3L2 protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 10% Glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Chitinase 3 Like 2

Entrez Gene ID

1117

UniProt ID

Q15782

Alternative Names

Cytochrome C, Somatic; CYC; Cytochrome C; THC4; HCS;

Function

Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.

Biological Process

Carbohydrate metabolic process Source: InterPro
Chitin catabolic process Source: GO_Central

Cellular Location

Secreted

Ogunkolade, B. W., Adaikalakoteswari, A., Cardoso, S. R., Lowe, R., Patel, N., Rakyan, V., ... & Hitman, G. A. (2021). An integrative epi-transcriptomic approach identifies the human cartilage chitinase 3-like protein 2 (CHI3L2) as a potential mediator of B12 deficiency in adipocytes. Epigenetics, 1-15.

Comabella, M., Sastre-Garriga, J., Borras, E., Villar, L. M., Saiz, A., Martínez-Yélamos, S., ... & Montalban, X. (2021). CSF Chitinase 3–Like 2 Is Associated With Long-term Disability Progression in Patients With Progressive Multiple Sclerosis. Neurology-Neuroimmunology Neuroinflammation, 8(6).

Pusztai, C., Yusenko, M. V., Banyai, D., Szanto, A., & Kovacs, G. (2019). M2 macrophage marker chitinase 3-like 2 (CHI3L2) associates with progression of conventional renal cell carcinoma. Anticancer research, 39(12), 6939-6943.

Sanfilippo, C., Longo, A., Lazzara, F., Cambria, D., Distefano, G., Palumbo, M., ... & Di Rosa, M. (2017). CHI3L1 and CHI3L2 overexpression in motor cortex and spinal cord of sALS patients. Molecular and Cellular Neuroscience, 85, 162-169.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Rabbit Anti-CHI3L2 Recombinant Antibody (CBFYC-1833) (CAT#: CBMAB-C1897-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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