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Mouse Anti-Chikungunya E2 Recombinant Antibody (AG52) (V2LY-0524-LY66)


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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
AG52
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC, In Vivo, Neutralization

Basic Information

Immunogen
Chikungunya E2 protein
Host Species
Mouse
Specificity
Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Endotoxin
< 1.0 EU/mg as determined by the LAL method
Format
Liquid
Buffer
PBS
Preservative
None
Concentration
5 mg/ml
Purity
>95% by SDS Page
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Chikungunya E2
Introduction
The Chikungunya virus, also known as the mosquitotransmitted alphavirus that causes global epidemics1, has been declared a serious disease by the CDC1. CHIKV is an enveloped virus with an 11.8-kb single-stranded, positive-sense RNA genome with two open reading frames3,4. The amino acid identity of the three main genotypes is 95.2 to 99.8%: Asian, West African, and East Central South African. A nucleocapsid protein C and two glycoproteines, E1 and E2, 5 are present in the mature CHIKV infection. E1's involved in the fusion of viruses. E2 is used for attachment to cells. E1 and E2 form 80 trimeric spikes on the virus surface 6.
Alternative Names
Chikungunya E2
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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