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Mouse Anti-CHORDC1 Recombinant Antibody (CBYY-C3165) (CBMAB-C4608-YY)

This product is mouse antibody that recognizes CHORDC1. The antibody CBYY-C3165 can be used for immunoassay techniques such as: ELISA, WB
See all CHORDC1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C3165
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
CHORDC1 (AAH08373, 1 a.a. ~ 66 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative
PBS
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cysteine And Histidine Rich Domain Containing 1
Entrez Gene ID
26973
UniProt ID
Q9UHD1
Alternative Names
AHUS5, ARMD9, ASPa, C3b, CPAMD1, HEL-S-62p, C3
Function
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2 (PubMed:20230755).
Proposed to act as co-chaperone for HSP90 (PubMed:20230755).
May play a role in the regulation of NOD1 via a HSP90 chaperone complex (PubMed:20230755).
In vitro, has intrinsic chaperone activity (PubMed:20230755).
This function may be achieved by inhibiting association of ROCK2 with NPM1 (PubMed:20230755).
Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling (PubMed:32053105).
Involved in stress response (PubMed:20230755).
Prevents tumorigenesis (PubMed:20230755).
Biological Process
Centrosome duplication Source: GO_Central
Chaperone-mediated protein folding Source: UniProtKB
Negative regulation of Rho-dependent protein serine/threonine kinase activity Source: Ensembl
Regulation of cellular response to heat Source: UniProtKB
Regulation of centrosome duplication Source: Ensembl
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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