Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-CHST5 Recombinant Antibody (2E6) (CBMAB-C5016-LY)


See all CHST5 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E6
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa310-391 from CHST5.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
Introduction
The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]
Entrez Gene ID
23563
UniProt ID
Q9GZS9
Alternative Names
Carbohydrate Sulfotransferase 5; Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 4-Alpha; Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 5; N-Acetylglucosamine 6-O-Sulfotransferase 3; Intestinal GlcNAc-6-Sulfotransferase; GlcNAc6ST-3; I-GlcNAc6ST; GST4-Alpha;
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates. However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for SELL. Its substrate specificity may be influenced by its subcellular location.
Biological Process
Carbohydrate metabolic process Source: UniProtKB-KW
Keratan sulfate biosynthetic process Source: GO_Central
N-acetylglucosamine metabolic process Source: UniProtKB
Protein sulfation Source: ProtInc
Sulfur compound metabolic process Source: UniProtKB
Cellular Location
Golgi apparatus membrane. Golgi membrane, early secretory pathway.
Topology
Cytoplasmic: 1-30
Helical: 31-48
Lumenal: 49-411
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CHST5 Recombinant Antibody (2E6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry