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Rabbit Anti-CINP Recombinant Antibody (CBWJC-2718) (CBMAB-C3813WJ)

This product is a Rabbit antibody that recognizes CINP. This antibody CBWJC-2718 can be used for immunoassay techniques such as: WB, IP, ICC.
See all CINP antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBWJC-2718
Antibody Isotype
IgG
Application
WB, IP, ICC

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.564 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cyclin Dependent Kinase 2 Interacting Protein
Introduction
The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Entrez Gene ID
Human51550
Mouse67236
Rat299334
UniProt ID
HumanQ9BW66
MouseQ9D0V8
RatB0BNM8
Alternative Names
Cyclin Dependent Kinase 2 Interacting Protein; CDK2-Interacting Protein;
Function
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
DNA repair Source: UniProtKB-KW
DNA replication Source: UniProtKB-KW
Cellular Location
Nucleus. Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
PTM
Phosphorylated by CDC7 but not by CDK2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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