Human Anti-CLEC4C Recombinant Antibody (
7B8) (V2LY-0725-LY1412)

Name: Human Anti-CLEC4C Recombinant Antibody (7B8)
SKU: V2LY-0725-LY1412
Rating: 5 (1 reviews)

See all CLEC4C antibodies

Compare Online Inquiry

Tested Data

Human Anti-CLEC4C Recombinant Antibody (7B8) (V2LY-0725-LY1412) in ELISA

The Binding Activity of CLEC4C with anti-CLEC4C antibodyActivity: Measured by its binding ability in a functional ELISA. Immobilized Human CLEC4C at 2 μg/mL can bind Anti-CLEC4C recombinant antibody,the EC50 is 7.658-12.99 ng/mL.

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Human

Clone

7B8

Application

ELISA

Immunogen

Recombinant Human CLEC4C protein.

Host Species

Human

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, Glycerol

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

C-Type Lectin Domain Family 4 Member C

Entrez Gene ID

170482

UniProt ID

Q8WTT0

Function

Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed:11748283, PubMed:21880719, PubMed:25995448).

Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed:21880719, PubMed:25995448).

Binds to serum IgG (PubMed:25995448).

Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells (PubMed:11748283).

May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed:11748283, PubMed:21880719).

May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed:11748283).

Biological Process

Adaptive immune response Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Neutrophil degranulation Source: Reactome
Stimulatory C-type lectin receptor signaling pathway Source: Reactome

Cellular Location

Cell membrane

Topology

Cytoplasmic: 1-21
Helical: 22-44
Extracellular: 45-213

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Anti-CLEC4C Recombinant Antibody (
7B8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Human CLEC4C ELISA Kit (CAT#: V2LY-0626-LY4452)

Human Recombinant CLEC4C protein, ECD, hFc Tag (CAT#: V2LY-0526-LY3223)

Mouse Anti-CLEC4C Recombinant Antibody (CBFYC-0424) (CAT#: V2LY-1206-LY136)

Human Anti-CLEC4C Recombinant Antibody (CBWJC-2040) (CAT#: V2LY-1206-LY137)

Mouse Anti-CLEC4C Recombinant Antibody (CBT4496) (CAT#: V2LY-0625-LY1554)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry