Mouse Anti-CLEC4M Recombinant Antibody (CBFYC-1930) (V2LY-1206-LY164)

Name: Mouse Anti-CLEC4M Recombinant Antibody (CBFYC-1930)
SKU: V2LY-1206-LY164
Rating: 5 (1 reviews)

See all CLEC4M antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYC-1930

Application

WB, IP, IF, ELISA, IHC-P

Immunogen

Amino acids 12-41 near the N-terminus of DC-SIGNR of human.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000
IHC-P	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

0.1% gelatin

Preservative

<0.1% sodium azide

Concentration

0.2 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

C-Type Lectin Domain Family 4 Member M

Entrez Gene ID

10332

UniProt ID

Q9H2X3

Function

Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

(Microbial infection) Acts as an attachment receptor for Ebolavirus.

(Microbial infection) Acts as an attachment receptor for Hepatitis C virus.

(Microbial infection) Acts as an attachment receptor for HIV-1.

(Microbial infection) Acts as an attachment receptor for Human coronavirus 229E.

(Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5.

(Microbial infection) Acts as an attachment receptor for Influenzavirus.

(Microbial infection) Acts as an attachment receptor for SARS-CoV.

(Microbial infection) Acts as an attachment receptor for West-nile virus.

(Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus.

(Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein.

(Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.

Biological Process

Adaptive immune response Source: UniProtKB-KW
Antigen processing and presentation Source: UniProtKB
Cell-cell recognition Source: UniProtKB
Endocytosis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Intracellular signal transduction Source: UniProtKB
Intracellular transport of virus Source: UniProtKB
Leukocyte cell-cell adhesion Source: UniProtKB
Modulation by virus of host process Source: UniProtKB
Peptide antigen transport Source: UniProtKB
Viral entry into host cell Source: FlyBase
Viral genome replication Source: UniProtKB
Virion attachment to host cell Source: UniProtKB

Cellular Location

Isoform 1&2&3: Cell membrane
Isoform 5&6&7&10: Secreted

Topology

Cytoplasmic: 1-49
Helical: 50-70
Extracellular: 71-399

Swystun, L. L., Notley, C., Georgescu, I., Lai, J. D., Nesbitt, K., James, P. D., & Lillicrap, D. (2019). The endothelial lectin clearance receptor CLEC 4M binds and internalizes factor VIII in a VWF‐dependent and independent manner. Journal of Thrombosis and Haemostasis, 17(4), 681-694.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-CLEC4M Recombinant Antibody (CBFYC-1930)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CLEC4M Recombinant Antibody (D0097) (CAT#: V2LY-1206-LY157)

Mouse Anti-CLEC4M Recombinant Antibody (CBXC-0467) (CAT#: V2LY-1206-LY165)

Mouse Anti-CLEC4M Recombinant Antibody (CBFYC-1929) (CAT#: V2LY-1206-LY163)

Mouse Anti-CLEC4M Recombinant Antibody (D0095) (CAT#: V2LY-1206-LY156)

Mouse Anti-CLEC4M Recombinant Antibody (D0093) (CAT#: V2LY-1206-LY155)

Human Recombinant CD299 proteinECD (CAT#: V2LY-0526-LY3512)

Mouse Anti-CLEC4M Recombinant Antibody (C11031) (CAT#: V2LY-1206-LY166)

Mouse Anti-CLEC4M Recombinant Antibody (CBFYC-1928) (CAT#: V2LY-1206-LY162)

Human Recombinant CD299 protein, hFc Tag (CAT#: V2LY-0526-LY3513)

Rabbit Anti-CLEC4M Recombinant Antibody (16E7) (CAT#: V2LY-1206-LY160)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry