Mouse Anti-CMBL Recombinant Antibody (CAP1021) (CBMAB-AP1558LY)

Name: Mouse Anti-CMBL Recombinant Antibody (CAP1021)
SKU: CBMAB-AP1558LY
Rating: 5 (1 reviews)

See all CMBL antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CAP1021

Application

ELISA, WB

Immunogen

Recombinant human CMBL (1-245aa) purified from E. coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
ELISA	1:100-1:2,000
WB	1:500-1:5,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 10% Glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Carboxymethylenebutenolidase Homolog

Introduction

CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]

Entrez Gene ID

134147

UniProt ID

Q96DG6

Alternative Names

Carboxymethylenebutenolidase Homolog; Carboxymethylenebutenolidase Homolog (Pseudomonas); Carboxymethylenebutenolidase-Like (Pseudomonas); EC 3.1.-.-; JS-1;

Function

Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.

Biological Process

Xenobiotic metabolic process Source: Reactome

Cellular Location

Cytosol

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-CMBL Recombinant Antibody (CAP1021)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CMBL Recombinant Antibody (C11060) (CAT#: V2LY-1206-LY351)

Mouse Anti-CMBL Recombinant Antibody (CBFYC-0520) (CAT#: V2LY-1206-LY349)

Mouse Anti-CMBL Recombinant Antibody (CBWJC-2836) (CAT#: CBMAB-C3958WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry