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CMBL

CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]

Anti-CMBL antibodies

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Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-C0821-LY Anti-CMBL Recombinant Antibody (2B11) CMBL IgG2a, κ Human 2B11 WB, E
CBMAB-C3958WJ Mouse Anti-CMBL Recombinant Antibody (CBWJC-2836) CMBL Mouse IgG Mouse, Rat, Human CBWJC-2836 WB, IP, IF, E
CBMAB-C3957WJ Mouse Anti-CMBL Recombinant Antibody (AT2B11) CMBL Mouse IgG2a, κ Human AT2B11 E, WB
CBMAB-C0571-FY Mouse Anti-CMBL (AA 1-245) Recombinant Antibody (CBFYC-0520) CMBL Mouse IgG2a, κ Human CBFYC-0520 WB, E
CBMAB-C3355-LY Mouse Anti-CMBL Recombinant Antibody (16C30) CMBL Mouse IgG Human 16C30 E, WB
CBMAB-C11059-LY Mouse Anti-CMBL Recombinant Antibody (CBLC164-LY) CMBL Mouse IgG Mouse, Rat, Human CBLC164-LY WB, IP, IF, E
CBMAB-C11060-LY Mouse Anti-CMBL Recombinant Antibody (PAT2B11AT) CMBL Mouse IgG2 Human PAT2B11AT E
PEP-148811CQ Human CMBL Peptide (REISAILKY) CMBL
PEP-148810CQ Human CMBL Peptide (AQKIGIVGF) CMBL
PEP-148809CQ Human CMBL Peptide (AVHHLMMKY) CMBL
PEP-148808CQ Human CMBL Peptide (NGYTTIVPDF) CMBL
PEP-148807CQ Human CMBL Peptide (IYNLKNPTLF) CMBL
PEP-148806CQ Human CMBL Peptide (IYNLKNPTL) CMBL
PEP-148805CQ Human CMBL Peptide (GYTTIVPDF) CMBL
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)