Mouse Anti-CPA3 Recombinant Antibody (2D1) (V2LY-1206-LY920)

Go to compare Compare Online Inquiry
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
2D1
Application
ELISA
Immunogen
CPA3 (aa318-417) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
carboxypeptidase A3 (mast cell)
Entrez Gene ID
UniProt ID
Biological Process
Angiotensin maturation Source: Reactome
Proteolysis Source: GO_Central
Cellular Location
Secretory vesicle. Secretory granules.

Akula, S., Hellman, L., Avilés, F. X., & Wernersson, S. (2022). Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases. Developmental & Comparative Immunology, 127, 104273.

Atiakshin, D., Kostin, A., Trotsenko, I., Samoilova, V., Buchwalow, I., & Tiemann, M. (2022). Carboxypeptidase A3—A Key Component of the Protease Phenotype of Mast Cells. Cells, 11(3), 570.

Siddhuraj, P., Clausson, C. M., Sanden, C., Alyamani, M., Kadivar, M., Marsal, J., ... & Erjefält, J. S. (2021). Lung mast cells have a high constitutive expression of carboxypeptidase A3 mRNA that is independent from granule-stored CPA3. Cells, 10(2), 309.

Soria‐Castro, R., Meneses‐Preza, Y. G., Rodríguez‐López, G. M., Romero‐Ramírez, S., Sosa‐Hernández, V. A., Cervantes‐Díaz, R., ... & Chacón‐Salinas, R. (2021). Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin. Journal of leukocyte biology, 110(3), 425-431.

Hämäläinen, S., Kareinen, L., Sukura, A., & Kareinen, I. (2021). Carboxypeptidase A3 expression in canine mast cell tumors and tissue-resident mast cells. Veterinary pathology, 03009858211062636.

Magnúsdóttir, E. I., Grujic, M., Bergman, J., Pejler, G., & Lagerström, M. C. (2020). Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1. Journal of neuroinflammation, 17(1), 1-11.

Lewicki, Ł., Siebert, J., Koliński, T., Piekarska, K., Reiwer-Gostomska, M., Targoński, R., ... & Marek-Trzonkowska, N. (2019). Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease. Cardiology Journal, 26(6), 680-686.

Abadalkareem, R., Lau, L. C., Abdelmotelb, A., Zhou, X., Eren, E., & Walls, A. F. (2017). Mast cell tryptase and carboxypeptidase A3 (CPA3) as markers for predicting susceptibility to severe allergic drug reactions. Journal of Allergy and Clinical Immunology, 139(2), AB39.

Grujic, M., Paivandy, A., Gustafson, A. M., Thomsen, A. R., Öhrvik, H., & Pejler, G. (2017). The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung. Oncotarget, 8(15), 25066.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-CPA3 Recombinant Antibody (2D1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.