Mouse Anti-CPM Recombinant Antibody (CBWJC-3023) (CBMAB-C4178WJ)

Name: Mouse Anti-CPM Recombinant Antibody (CBWJC-3023)
SKU: CBMAB-C4178WJ
Rating: 5 (1 reviews)

See all CPM antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBWJC-3023

Application

WB, IHC

Immunogen

Human recombinant protein fragment corresponding to aa124-423 of human CPM(NP_001865) produced in E.coli

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2b

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:2,000
IHC	1:150

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Carboxypeptidase M

Introduction

CPM (Carboxypeptidase M) is a Protein Coding gene. Diseases associated with CPM include Well-Differentiated Liposarcoma. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. Gene Ontology (GO) annotations related to this gene include hydrolase activity, acting on ester bonds and carboxypeptidase activity. An important paralog of this gene is CPD.

Entrez Gene ID

Human	1368
Mouse	70574
Rat	314855

UniProt ID

Human	P14384
Mouse	Q80V42
Rat	A6IGT0

Alternative Names

Carboxypeptidase M; Urinary Carboxypeptidase B; Renal Carboxypeptidase; EC 3.4.17.12; EC 3.4.17;

Function

Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

Biological Process

Anatomical structure morphogenesis Source: ProtInc
Peptide metabolic process Source: GO_Central
Protein processing Source: GO_Central

Cellular Location

Cell membrane

Mamoor, S. (2021). Differential expression of carboxypeptidase M in cancers of the breast.

Shi, L., Liu, L., Lv, X., Ma, Z., Li, C., Li, Y., ... & Han, B. (2020). Identification of genetic effects and potential causal polymorphisms of CPM gene impacting milk fatty acid traits in Chinese Holstein. Animal Genetics, 51(4), 491-501.

Chu, M., Wu, S., Wang, W., Yu, Y., Zhang, M., Sang, L., ... & Wu, J. (2019). Functional variant of the carboxypeptidase M (CPM) gene may affect silica-related pneumoconiosis susceptibility by its expression: a multistage case–control study. Occupational and environmental medicine, 76(3), 169-174.

Guimarães, P. B., da Silva, R. F., Hoff, C. C., Fernandes, L., Nakaie, C. R., Chagas, J. R., ... & Pesquero, J. B. (2019). Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells. Inflammation Research, 68(10), 845-855.

Lu, D., Yao, Q., Zhan, C., Le-Meng, Z., Liu, H., Cai, Y., ... & Zhang, S. (2017). MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway. Oncotarget, 8(14), 22674.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-CPM Recombinant Antibody (CBWJC-3023)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CPM Recombinant Antibody (CBWJC-3018) (CAT#: V2LY-1206-LY968)

Mouse Anti-CPM Recombinant Antibody (CBXC-2006) (CAT#: V2LY-1206-LY966)

Mouse Anti-CPM Recombinant Antibody (CBXC-2077) (CAT#: CBMAB-C4459-CQ)

Mouse Anti-CPM Recombinant Antibody (CBXC-1337) (CAT#: V2LY-1206-LY965)

Rabbit Anti-CPM Recombinant Antibody (CBFYC-2159) (CAT#: V2LY-1206-LY963)

Mouse Anti-CPM Recombinant Antibody (1F8) (CAT#: V2LY-1206-LY962)

Rabbit Anti-CPM Recombinant Antibody (105) (CAT#: CBMAB-C2065-LY)

Mouse Anti-CPM Recombinant Antibody (CBYY-C2919) (CAT#: CBMAB-C4362-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry