Rabbit Anti-CRCP Recombinant Antibody (1428) (V2LY-1206-LY1081)

Name: Rabbit Anti-CRCP Recombinant Antibody (1428)
SKU: V2LY-1206-LY1081
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

1428

Application

WB, IF, IHC

Immunogen

Synthetic peptide within human CRCP aa 10-60/148.

Host Species

Rabbit

Specificity

Human, Mouse

Antibody Isotype

IgG

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500
IHC	1:100
IF(ICC)	1:200

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

TBS, pH7.4, 0.05% BSA, 40% Glycerol

Preservative

0.05% sodium azide

Concentration

1 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

CGRP Receptor Component

Entrez Gene ID

Human	27297
Mouse	12909

UniProt ID

Human	O75575
Mouse	O35427

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.

Biological Process

Defense response to virus Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Neuropeptide signaling pathway Source: Ensembl
Positive regulation of type I interferon production Source: Reactome
Transcription by RNA polymerase III Source: UniProtKB
Transcription initiation from RNA polymerase III promoter Source: GO_Central

Cellular Location

Cell membrane; Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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