Mouse Anti-CSNK1G1 Recombinant Antibody (CBFYC-2299) (CBMAB-C2371-FY)

Name: Mouse Anti-CSNK1G1 Recombinant Antibody (CBFYC-2299)
SKU: CBMAB-C2371-FY
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYC-2299

Antibody Isotype

IgG3, κ

Application

IHC-P, WB, ELISA

Basic Information

Immunogen

CSNK1G1 (293-393 aa) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG3, κ

Clonality

Monoclonal Antibody

Application Notes

Application	Note
IHC-P	3 μg/mL

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Target

Full Name

Casein Kinase 1 Gamma 1

Entrez Gene ID

53944

UniProt ID

Q9HCP0

Function

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).

Phosphorylates CLSPN.

Biological Process

Endocytosis Source: GO_Central
Peptidyl-serine phosphorylation Source: ParkinsonsUK-UCL
Positive regulation of canonical Wnt signaling pathway Source: GO_Central
Wnt signaling pathway Source: GO_Central

Cellular Location

Cytoplasm

PTM

Autophosphorylated.

More Infomation

References

Chen, H., Li, Q., Yi, R., Li, B., Xiong, D., & Peng, H. (2022). CircRNA casein kinase 1 gamma 1 (circ‐CSNK1G1) plays carcinogenic effects in thyroid cancer by acting as miR‐149‐5p sponge and relieving the suppression of miR‐149‐5p on mitogen‐activated protein kinase 1 (MAPK1). Journal of clinical laboratory analysis, e24188.

Agajanian, M. J., Potjewyd, F. M., Bowman, B. M., Solomon, S., LaPak, K. M., Bhatt, D. P., ... & Major, M. B. (2021). Protein proximity networks and functional evaluation of the Casein Kinase 1 γ family reveals unique roles for CK1γ3 in WNT signaling. bioRxiv.

Gold, N. B., Li, D., Chassevent, A., Kaiser, F. J., Parenti, I., Strom, T. M., ... & Bhoj, E. (2020). Heterozygous de novo variants in CSNK1G1 are associated with syndromic developmental delay and autism spectrum disorder. Clinical Genetics, 98(6), 571-576.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Antibody Pairs

CSNK1G1 Matched Antibody Pair (305)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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