Human Recombinant CSNK1G1 protein, GST Tag (V2LY-0526-LY3398)

Name: Human Recombinant CSNK1G1 protein, GST Tag
SKU: V2LY-0526-LY3398
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant CSNK1G1 protein, GST Tag consist of Amino Acid: 1-422 and predicts a molecular mass of 76.3 kDa.

Molecule Mass

76.3 kDa

Sequence

Amino Acid: 1-422

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥90% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Casein Kinase 1 Gamma 1

Function

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).

Phosphorylates CLSPN.

Biological Process

Endocytosis Source: GO_Central
Peptidyl-serine phosphorylation Source: ParkinsonsUK-UCL
Positive regulation of canonical Wnt signaling pathway Source: GO_Central
Wnt signaling pathway Source: GO_Central

Cellular Location

Cytoplasm

PTM

Autophosphorylated.

Chen, H., Li, Q., Yi, R., Li, B., Xiong, D., & Peng, H. (2022). CircRNA casein kinase 1 gamma 1 (circ‐CSNK1G1) plays carcinogenic effects in thyroid cancer by acting as miR‐149‐5p sponge and relieving the suppression of miR‐149‐5p on mitogen‐activated protein kinase 1 (MAPK1). Journal of clinical laboratory analysis, e24188.

Agajanian, M. J., Potjewyd, F. M., Bowman, B. M., Solomon, S., LaPak, K. M., Bhatt, D. P., ... & Major, M. B. (2021). Protein proximity networks and functional evaluation of the Casein Kinase 1 γ family reveals unique roles for CK1γ3 in WNT signaling. bioRxiv.

Gold, N. B., Li, D., Chassevent, A., Kaiser, F. J., Parenti, I., Strom, T. M., ... & Bhoj, E. (2020). Heterozygous de novo variants in CSNK1G1 are associated with syndromic developmental delay and autism spectrum disorder. Clinical Genetics, 98(6), 571-576.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

CSNK1G1 Matched Antibody Pair (305) (CAT#: APMAB-305LY)

Human Recombinant CSNK1G1, Active protein, GST Tag (CAT#: V2LY-0526-LY3397)

Antibody Pairs

CSNK1G1 Matched Antibody Pair (305) (CAT#: APMAB-305LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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