Mouse Anti-DAP3 Recombinant Antibody (D0213) (V2LY-0125-LY1091)

Name: Mouse Anti-DAP3 Recombinant Antibody (D0213)
SKU: V2LY-0125-LY1091
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human, Mouse

Clone

D0213

Antibody Isotype

IgG

Application

Basic Information

Immunogen

Amino acids 51-66 of human DAP-3.

Host Species

Mouse

Specificity

Human, Mouse

Antibody Isotype

IgG

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	3-5 μg/mL

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Gelatin & PBS

Preservative

Sodium Azide

Concentration

0.5 mg/mL

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

death associated protein 3

Entrez Gene ID

Human	7818
Mouse	65111

UniProt ID

Human	P51398
Mouse	Q9ER88

Function

Involved in mediating interferon-gamma-induced cell death.

Biological Process

Apoptotic signaling pathway Source: ProtInc
Mitochondrial translational elongation Source: Reactome
Mitochondrial translational termination Source: Reactome

Cellular Location

Mitochondrion

More Infomation

References

Sui, L., Ye, L., Sanders, A. J., Yang, Y., Hao, C., Hargest, R., & Jiang, W. G. (2021). Expression of death associated proteins DAP1 and DAP3 in human pancreatic cancer. Anticancer Research, 41(5), 2357-2362.

Sato, Y., Yoshino, H., Kashiwakura, I., & Tsuruga, E. (2021). DAP3 is involved in modulation of cellular radiation response by RIG-I-like receptor agonist in human lung adenocarcinoma cells. International Journal of Molecular Sciences, 22(1), 420.

Sui, L., Zeng, J., Ye, L., Sanders, A. J., Zhao, H., Jiang, A., ... & Jiang, W. G. (2021). PTH-100 DAP3 and the DAP3 Binding Cell Death Enhancer-1 (DELE1) in human colorectal cancer.

Han, J., An, O., Hong, H., Chan, T. H. M., Song, Y., Shen, H., ... & Chen, L. (2020). Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression. Science advances, 6(25), eaba5136.

Jia, Y., Li, Z., Cheng, X., Wu, X., Pang, F., Shi, J., ... & Ji, J. (2019). Depletion of death-associated protein-3 induces chemoresistance in gastric cancer cells through the β-catenin/LGR5/Bcl-2 axis. Journal of Investigative Medicine, 67(5), 856-861.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

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Mouse Anti-DAP3 Recombinant Antibody (1A12)

Mouse Anti-DAP3 Recombinant Antibody (D0210)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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