Rabbit Anti-DDX39A Recombinant Antibody (D0548) (V2LY-0425-LY46)

Name: Rabbit Anti-DDX39A Recombinant Antibody (D0548)
SKU: V2LY-0425-LY46
Rating: 5 (1 reviews)

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Summary

Host Animal

Rabbit

Specificity

Human, Mouse, Rat, Monkey

Clone

D0548

Antibody Isotype

IgG

Application

WB, IP

Basic Information

Immunogen

Synthetic peptide corresponding to residues surrounding Pro22 of human DDX39A protein.

Host Species

Rabbit

Specificity

Human, Mouse, Rat, Monkey

Antibody Isotype

IgG

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:1,000
IP	1:50

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

BSA & Glycerol & HEPES

Preservative

Sodium Azide

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

DExD-Box Helicase 39A

Entrez Gene ID

10212

UniProt ID

O00148

Function

Isoform 1:
Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus.

Biological Process

mRNA 3'-end processing Source: Reactome
mRNA export from nucleus Source: UniProtKB
mRNA splicing, via spliceosome Source: UniProtKB
RNA export from nucleus Source: Reactome

Cellular Location

Nucleus; Cytoplasm. Can translocate to the cytoplasm in the presence of MX1.

More Infomation

References

Saleem, I., Mirza, S., Sarkar, A., Raza, M., Mohapatra, B., Mushtaq, I., ... & Band, V. (2021). The mammalian ecdysoneless protein interacts with RNA helicase DDX39A to regulate nuclear mRNA export. Molecular and cellular biology, 41(7), e00103-21.

Shi, P., Guo, Y., Su, Y., Zhu, M., Fu, Y., Chi, H., ... & Huang, J. (2020). SUMOylation of DDX39A alters binding and export of antiviral transcripts to control innate immunity. The Journal of Immunology, 205(1), 168-180.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-DDX39A Recombinant Antibody (2252C4a)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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