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Mouse Anti-DDX54 Recombinant Antibody (5B3) (CBMAB-D0595-YC)

Provided herein is a Mouse monoclonal antibody, which binds to DEAD-Box Helicase 54 (DDX54). The antibody can be used for immunoassay techniques, such as WB.
See all DDX54 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5B3
Antibody Isotype
IgG2a, κ
Application
WB

Basic Information

Immunogen
DDX54 (NP_076977, 778 a.a. ~ 882 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DEAD-Box Helicase 54
Introduction
DDX54 belongs to the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.
Entrez Gene ID
79039
UniProt ID
Q8TDD1
Alternative Names
DEAD-Box Helicase 54; DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 54; ATP-Dependent RNA Helicase DP97; DEAD Box RNA Helicase 97 KDa; DEAD Box Protein 54; ATP-Dependent RNA Helicase DDX54;
Function
Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.
Biological Process
Intracellular estrogen receptor signaling pathway Source: UniProtKB
RNA metabolic process Source: UniProtKB
RNA processing Source: UniProtKB
rRNA processing Source: GO_Central
Cellular Location
Nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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