DDX54

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
DEAD-Box Helicase 54
Function
Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.
Biological Process
Intracellular estrogen receptor signaling pathway Source: UniProtKB
RNA metabolic process Source: UniProtKB
RNA processing Source: UniProtKB
rRNA processing Source: GO_Central
Cellular Location
Nucleolus
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Anti-DDX54 antibodies

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Target: DDX54
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: D0596
Application*: WB, IH
Target: DDX54
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5B3
Application*: E, WB
Target: DDX54
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2H6
Application*: E, IF, P, WB
Target: DDX54
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E4
Application*: E, P, WB
Target: DDX54
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5B3
Application*: WB
Target: DDX54
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2H6
Application*: E, IF, P, WB
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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