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Mouse Anti-DECR2 Recombinant Antibody (4A7) (CBMAB-D0653-YC)

Provided herein is a Mouse monoclonal antibody, which binds to 2,4-Dienoyl-CoA Reductase 2 (DECR2). The antibody can be used for immunoassay techniques, such as WB.
See all DECR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4A7
Antibody Isotype
IgG2a, κ
Application
WB

Basic Information

Immunogen
DECR2 (AAH10740, 49 a.a. ~ 109 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
2,4-Dienoyl-CoA Reductase 2
Introduction
DECR2 (2,4-Dienoyl-CoA Reductase 2) is a protein coding gene. Among its related pathways are Metabolism and Peroxisome. It has proved that the protein has receptor binding and 2,4-dienoyl-CoA reductase (NADPH) activity. And a paralog is DECR1.
Entrez Gene ID
26063
UniProt ID
Q9NUI1
Alternative Names
2,4-Dienoyl-CoA Reductase 2; Short Chain Dehydrogenase/Reductase Family 17C Member 1; 2,4-Dienoyl-CoA Reductase 2, Peroxisomal; EC 1.3.1.34; SDR17C1; PDCR; Short Chain Dehydrogenase/Reductase Family 17C, Member 1; Peroxisomal 2,4-Dienoyl-CoA Reductase; EC 1.3.1;
Function
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Biological Process
Fatty acid beta-oxidation using acyl-CoA oxidase Source: Reactome
Protein localization Source: Reactome
Unsaturated fatty acid biosynthetic process Source: UniProtKB
Cellular Location
Peroxisome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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