Mouse Anti-DEFA6 Recombinant Antibody (2D2) (V2LY-0425-LY158)

Name: Mouse Anti-DEFA6 Recombinant Antibody (2D2)
SKU: V2LY-0425-LY158
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2D2

Application

ELISA, WB

Immunogen

DEFA6 full-length recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

defensin, alpha 6, Paneth cell-specific

Entrez Gene ID

1671

UniProt ID

Q01524

Function

Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.

Biological Process

Antibacterial humoral response Source: GO_Central
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: GO_Central
Antimicrobial humoral response Source: Reactome
Cellular response to lipopolysaccharide Source: GO_Central
Defense response to fungus Source: UniProtKB-KW
Defense response to Gram-negative bacterium Source: GO_Central
Defense response to Gram-positive bacterium Source: GO_Central
Innate immune response in mucosa Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Membrane disruption in other organism Source: GO_Central

Cellular Location

Secreted

Wei, P. L., Lin, J. C., Hung, C. S., Makondi, P. T., Batzorig, U., Chang, T. C., ... & Chang, Y. J. (2022). Human α-defensin 6 (HD6) suppresses CRC proliferation and metastasis through abolished EGF/EGFR signaling pathway. International journal of medical sciences, 19(1), 34.

Jeong, D., Kim, H., Kim, D., Ban, S., Oh, S., Ji, S., ... & Baek, M. J. (2019). Defensin alpha 6 (DEFA6) is a prognostic marker in colorectal cancer. Cancer Biomarkers, 24(4), 485-495.

Markasz, L., Wanders, A., Szekely, L., & Lilja, H. E. (2018). Diminished DEFA6 expression in paneth cells is associated with necrotizing enterocolitis. Gastroenterology Research and Practice, 2018.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

Mouse Anti-DEFA6 Recombinant Antibody (2D2) (CAT#: CBMAB-D0680-YC)

Related Products

Mouse Anti-DEFA6 Recombinant Antibody (2D2) (CAT#: CBMAB-D0680-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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