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Mouse Anti-DIMT1 Recombinant Antibody (D0932) (V2LY-0425-LY355)

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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
D0932
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 1-238 of human DIMT1L produced in E.coli.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
BSA & Glycerol & PBS
Preservative
Sodium Azide
Concentration
1 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DIM1 Dimethyladenosine Transferase 1 Homolog
Entrez Gene ID
Human27292
Mouse66254
Rat294718
UniProt ID
HumanQ9UNQ2
MouseQ9D0D4
RatG3V7R8
Function
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (PubMed:25851604).

Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604).
Biological Process
Positive regulation of rRNA processing Source: UniProtKB
rRNA methylation Source: UniProtKB
Cellular Location
Nucleoplasm; Nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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