Mouse Anti-DIRAS2 Recombinant Antibody (10H1) (CBMAB-D0935-YC)

Name: Mouse Anti-DIRAS2 Recombinant Antibody (10H1)
SKU: CBMAB-D0935-YC
Rating: 5 (1 reviews)

See all DIRAS2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

10H1

Application

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-196 of human DIRAS2 (NP_060064) produced in E.coli

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

DIRAS Family GTPase 2

Introduction

DIRAS2 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases.

Entrez Gene ID

54769

UniProt ID

Q96HU8

Alternative Names

DIRAS Family GTPase 2; Distinct Subgroup Of The Ras Family Member 2; DIRAS Family, GTP-Binding RAS-Like 2; GTP-Binding Protein Di-Ras2; Di-Ras2;

Function

Displays low GTPase activity and exists predominantly in the GTP-bound form.

Biological Process

Signal transduction Source: InterPro

Cellular Location

Cell membrane

Ying, K., Wang, C., Liu, S., Kuang, Y., Tao, Q., & Hu, X. (2022). Diverse Ras-related GTPase DIRAS2, downregulated by PSMD2 in a proteasome-mediated way, inhibits colorectal cancer proliferation by blocking NF-κB signaling. International Journal of Biological Sciences, 18(3), 1039.

Rothhammer-Hampl, T., Liesenberg, F., Hansen, N., Hoja, S., Delic, S., Reifenberger, G., & Riemenschneider, M. J. (2021). Frequent Epigenetic Inactivation of DIRAS-1 and DIRAS-2 Contributes to Chemo-Resistance in Gliomas. Cancers, 13(20), 5113.

Li, X., Liu, S., Fang, X., He, C., & Hu, X. (2019). The mechanisms of DIRAS family members in role of tumor suppressor. Journal of cellular physiology, 234(5), 5564-5577.

Sutton, M. N., Yang, H., Huang, G. Y., Fu, C., Pontikos, M., Wang, Y., ... & Bast Jr, R. C. (2018). RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells. Autophagy, 14(4), 637-653.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-DIRAS2 Recombinant Antibody (10H1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

Mouse Anti-DIRAS2 Recombinant Antibody (10H1) (CAT#: V2LY-0425-LY361)

Related Products

Mouse Anti-DIRAS2 Recombinant Antibody (10H1) (CAT#: V2LY-0425-LY361)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry