Mouse Anti-DNAH14 Recombinant Antibody (3C12) (CBMAB-D1243-YC)

Name: Mouse Anti-DNAH14 Recombinant Antibody (3C12)
SKU: CBMAB-D1243-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3C12

Application

ELISA

Immunogen

MGC27277 (AAH42869, 1 a.a. ~ 189 a.a) full-length recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Dynein Axonemal Heavy Chain 14

Introduction

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC).

Entrez Gene ID

127602

UniProt ID

Q0VDD8

Alternative Names

Dynein Axonemal Heavy Chain 14; Dynein, Axonemal, Heavy Polypeptide 14; Axonemal Beta Dynein Heavy Chain 14; Ciliary Dynein Heavy Chain 14; C1orf67; Chromosome 1 Open Reading Frame 67;

Function

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).

Biological Process

Cilium-dependent cell motility Source: InterPro
Microtubule-based movement Source: GO_Central

Cellular Location

Cilium axoneme

Li, J., Yuan, Y., Liu, C., Xu, Y., Xiao, N., Long, H., ... & Long, L. (2022). DNAH14 variants are associated with neurodevelopmental disorders. Human Mutation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-DNAH14 Recombinant Antibody (3C12) (CAT#: V2LY-0425-LY602)

Related Products

Mouse Anti-DNAH14 Recombinant Antibody (3C12) (CAT#: V2LY-0425-LY602)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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