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Mouse Anti-DNAH14 Recombinant Antibody (3C12) (CBMAB-D1243-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dynein Axonemal Heavy Chain 14 (DNAH14). The antibody can be used for immunoassay techniques, such as ELISA.
See all DNAH14 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3C12
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
MGC27277 (AAH42869, 1 a.a. ~ 189 a.a) full-length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Dynein Axonemal Heavy Chain 14
Introduction
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC).
Entrez Gene ID
127602
UniProt ID
Q0VDD8
Alternative Names
Dynein Axonemal Heavy Chain 14; Dynein, Axonemal, Heavy Polypeptide 14; Axonemal Beta Dynein Heavy Chain 14; Ciliary Dynein Heavy Chain 14; C1orf67; Chromosome 1 Open Reading Frame 67;
Function
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).
Biological Process
Cilium-dependent cell motility Source: InterPro
Microtubule-based movement Source: GO_Central
Cellular Location
Cilium axoneme
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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