DNAH14

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]

Full Name

Dynein Axonemal Heavy Chain 14

Function

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).

Biological Process

Cilium-dependent cell motility Source: InterPro
Microtubule-based movement Source: GO_Central

Cellular Location

Cilium axoneme

Anti-DNAH14 antibodies

Mouse Anti-DNAH14 Recombinant Antibody (3C12) (CBMAB-D1243-YC)

Datasheet

SDS

Target: DNAH14

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3C12

Application*: E

Mouse Anti-DNAH14 Recombinant Antibody (CBYCD-328) (CBMAB-D1244-YC)

Datasheet

SDS

Target: DNAH14

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYCD-328

Application*: E, WB

Mouse Anti-DNAH14 Recombinant Antibody (CBLC210-LY) (CBMAB-C11469-LY)

Datasheet

SDS

Target: DNAH14

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBLC210-LY

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)