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Mouse Anti-DNAJC24 Recombinant Antibody (CBWJZ-059) (CBMAB-Z0128-WJ)

This product is a mouse antibody that recognizes DNAJC24. The antibody CBWJZ-059 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all DNAJC24 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJZ-059
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
DnaJ Heat Shock Protein Family (Hsp40) Member C24
Introduction
DNAJC24 (DnaJ Heat Shock Protein Family (Hsp40) Member C24) is a Protein Coding gene. Diseases associated with DNAJC24 include Diphtheria and Aniridia 1. Among its related pathways are Metabolism of proteins and Gamma carboxylation, hypusine formation and arylsulfatase activation. Gene Ontology (GO) annotations related to this gene include ferrous iron binding and ATPase activator activity.
Entrez Gene ID
120526
UniProt ID
Q6P3W2
Alternative Names
DPH4; JJJ3; ZCSL3
Function
Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
Biological Process
Chaperone-mediated protein folding Source: UniProtKB
Peptidyl-diphthamide biosynthetic process from peptidyl-histidine Source: UniProtKB-UniPathway
Positive regulation of ATPase activity Source: UniProtKB
Cellular Location
Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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