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Mouse Anti-DNTTIP1 Recombinant Antibody (1H8) (CBMAB-D1465-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1H8
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human DNTTIP1 (NP_443183) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Deoxynucleotidyltransferase Terminal Interacting Protein 1
Introduction
DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase, a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template.
Entrez Gene ID
116092
UniProt ID
Q9H147
Alternative Names
Deoxynucleotidyltransferase Terminal Interacting Protein 1; Terminal Deoxynucleotidyltransferase-Interacting Factor 1; TdT-Interacting Factor 1; TdT Binding Protein; C20orf167; Tdif1;
Function
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582).

Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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