Mouse Anti-DNTTIP1 Recombinant Antibody (CBYJT-1199) (CBMAB-T0213-YJ)

Name: Mouse Anti-DNTTIP1 Recombinant Antibody (CBYJT-1199)
SKU: CBMAB-T0213-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJT-1199

Application

ICC, WB

Immunogen

Partial sequence of recombinant full-length protein to human Terminal Deoxynucleotidyltransferase Interacting Protein 1

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4, 1% BSA

Preservative

0.05% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Deoxynucleotidyltransferase Terminal Interacting Protein 1

Introduction

DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).

Entrez Gene ID

116092

UniProt ID

Q9H147

Alternative Names

Deoxynucleotidyltransferase Terminal Interacting Protein 1; Terminal Deoxynucleotidyltransferase-Interacting Factor 1; TdT-Interacting Factor 1; TdT Binding Protein; C20orf167; Tdif1

Function

Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582).

Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.

Cellular Location

Nucleus

Zhu, C., Tong, R., Jiang, X., Xiao, H., Guan, J., & Shu, J. (2021). DNTTIP1 is a Prognostic Biomarker Correlated With Immune Infiltrates in Hepatocellular Carcinoma: A Study Based on The Cancer Genome Atlas Data. Frontiers in genetics, 12, 767834-767834.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

Mouse Anti-DNTTIP1 Recombinant Antibody (CBYJT-1199) (CAT#: V2LY-0425-LY761)

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Mouse Anti-DNTTIP1 Recombinant Antibody (1F4) (CAT#: CBMAB-D1464-YC)

Mouse Anti-DNTTIP1 Recombinant Antibody (1H8) (CAT#: V2LY-0425-LY760)

Mouse Anti-DNTTIP1 Recombinant Antibody (CBYJT-1199) (CAT#: V2LY-0425-LY761)

Mouse Anti-DNTTIP1 Recombinant Antibody (1F4) (CAT#: V2LY-0425-LY759)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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