Mouse Anti-DPEP3 Recombinant Antibody (F-3) (CBMAB-D1543-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dipeptidase 3 (DPEP3). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all DPEP3 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

F-3

Antibody Isotype

IgG

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

dipeptidase 3

Introduction

DPEP3 is a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Entrez Gene ID

64180

UniProt ID

Q9H4B8

Alternative Names

Dipeptidase 3; EC 3.4.13.19; Testis Secretory Sperm-Binding Protein Li 211a; Metallopeptidase (Family M19); Membrane-Bound Dipeptidase 3; MBD3;

Function

Dipeptidase that hydrolyzes cystinyl-bis-glycine. Does not hydrolyze leukotriene D4 (LTD4) into leukotriene E4 (LTE4).

Cellular Location

Membrane

References

Hayashi, K., Longenecker, K. L., Koenig, P., Prashar, A., Hampl, J., Stoll, V., & Vivona, S. (2020). Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity. Journal of Structural Biology, 211(1), 107512.

Xie, Y., Khan, R., Wahab, F., Hussain, H. M. J., Ali, A., Ma, H., ... & Shi, Q. (2019). The testis-specifically expressed Dpep3 is not essential for male fertility in mice. Gene, 711, 143925.

Schiza, C., Korbakis, D., Panteleli, E., Jarvi, K., Drabovich, A. P., & Diamandis, E. P. (2018). Discovery of a human testis-specific protein complex TEX101-DPEP3 and selection of its disrupting antibodies. Molecular & Cellular Proteomics, 17(12), 2480-2495.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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